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Cholesterol Explained: HDL, LDL, Triglycerides, and Your Heart Health

Sunil Kalikayi3/26/20268 min read

What Is Cholesterol and Why Do We Have It

Cholesterol is essential: it builds cell membranes, produces steroid hormones (testosterone, estrogen, cortisol), makes bile acids, and enables vitamin D synthesis. The liver produces 75% of your cholesterol. Diet accounts for 25%.

HDL, LDL, and VLDL Explained

LDL (low-density lipoprotein): carries cholesterol to tissues; excess deposits in artery walls → atherosclerosis. HDL (high-density lipoprotein): carries cholesterol back to liver for elimination (reverse cholesterol transport) — protective. VLDL: very low density; primarily carries triglycerides.

Target Ranges

Total cholesterol: < 200 mg/dL optimal. LDL: < 100 mg/dL ideal; < 70 mg/dL for very high-risk patients. HDL: > 60 mg/dL protective; < 40 mg/dL (men) or < 50 mg/dL (women) is risk factor. Triglycerides: < 150 mg/dL optimal.

What Raises LDL

Saturated fat (main dietary driver). Trans fats (now largely banned but still in some processed foods). Genetics (familial hypercholesterolemia — LDL > 190 mg/dL). Hypothyroidism, kidney disease. Sedentary lifestyle.

Cardiovascular Risk Beyond Cholesterol

The Framingham Risk Score combines: age, gender, total cholesterol, HDL, systolic BP, smoking status, and diabetes. It estimates 10-year CVD risk. A person with "normal" cholesterol but several other factors may have higher risk than someone with elevated LDL but no other factors.

How to Improve Your Cholesterol Profile

LDL-lowering: Reduce saturated fat, increase soluble fiber (oats, legumes), plant sterols, statins if prescribed. HDL-raising: Exercise (most effective), quit smoking, reduce refined carbs. Triglycerides-lowering: Cut sugar and refined carbs, omega-3 fatty acids, lose weight.

Frequently Asked Questions

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